BDBM22853 1,2-Dione-Based Compound, 10::1,2-dihydroacenaphthylenedione

SMILES O=c1c2cccc3cccc(c23)c1=O

InChI Key InChIKey=AFPRJLBZLPBTPZ-UHFFFAOYSA-N

Data  7 KI  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22853   

TargetCoagulation factor XII(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22853(1,2-Dione-Based Compound, 10 | 1,2-dihydroacenapht...)
Affinity DataKi:  170nM ΔG°:  -9.23kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed